Note: All samples should be forwarded to LabPlus at room temperature within 24hours.
4 mL CPD Blood (Preferred) 4 mL EDTA Blood Turnaround Time: Within 2 weeks, 4 days Diagnostic Use and Interpretation
This test detects the Factor V Leiden mutation in the Factor V gene. The resultidentifies a heritable cause for APC resistance and thus can indicate an increased risk of thrombosis.
Prothrombin mutation analysis
To contact the Molecular Haematology team please call:
Auckland City Hospital (09) 307 4949 Lablink ext 22000 Prof. Peter Browett (Haematologist) ext 9090-86281 Nikhil Ghallayan (Section Leader) ext 22006 Molecular Haematology Lab ext 22005
For more inforamtion about the Molecular Haematology service at LabPLUS:
Molecular Haematology information page
A mutation in the factor V gene which changes arginine 506 to a glutamine does not affect the coagulation properties of factor V but renders the protein resistant to protein C degradation. This mutation leads to Protein C resistance and is hence a thrombosis risk factor.
Bertina RM et al. Nature, 1993, 369:64-67.