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Lactate dehydrogenase
Also known as : [LD],[LDH]


Plasma/Serum
Test performed by: LabPLUS Automation


Specimen Collection

If separation of blood is delayed for more than 3h, LDH leaks from red cells and falsely elevated LDH activity levels will be seen.

Sample stability:


PST

4.5 mL PST Blood (Preferred)

Micro-PST

0.5 mL Paediatric Micro-PST Blood (Preferred)

Heparin

5 mL Heparin Blood

Plain

4 mL Plain Blood

SST

3.5 mL SST Blood

Microsample

0.5 mL Paediatric Microsample Blood

Micro-heparin

0.5 mL Paediatric Micro-heparin Blood
Reference Intervals

Units: U/L

Reference interval: 120 - 250

Uncertainty of Measurement: 5%

Falsely high values can be caused by haemolysis or delayed separation of the sample.



Turnaround Time: Within 3 hours
Assay Method

Principle : Enzymatic

Reagents: Roche LDHI2 kit

Analyser: Cobas c502


Diagnostic Use and Interpretation

Sources of LDH:

The source of an elevated LDH of unknown cause can be identified by testing LDH isoenzymes.


Time course of enzyme changes after myocardial infarction


Starts to rise Peak Remain

Elevated

Myoglobin

2-4h

4-12h

15-40h

Troponin T

4-6h

12-24h

4-10d

Total CK and CKMB

4-6h

24-48h

3-5d

AST

6-8h

24-48h

4-6d

LD

12-24h

48-72h

7-12d


Contact Information

The chemical pathology team can be reached via email: chemicalpathologist@adhb.govt.nz or via Lablink (09) 307 4949 ext 22000 or 09-3078995

Emails will receive priority attention from the on-call chemical pathologist. Include the patients NHI.

After-hours: contact Lablink (Auckland City Hospital ext. 22000 or 09-3078995) or hospital operator for on duty staff after hours .




Last updated at 11:42:03 16/01/2026