Specimen Collection

NOTE:

Do not collect samples on a Friday, the weekend or the day falling immediately prior to a long weekend. These samples may be rejected and a re-collect required.

RNA is highly unstable and specimens degrade rapidly. For optimum results samples should be sent in CPD tubes at room temperature and be received by this lab within 24 hours of collection. Although LabPlus operates 24 hours a day, 7 days a week, the Molecular Haematology section only operates 9-5, Mon-Fri (excluding public holidays). Samples arriving on a Friday afternoon or a Saturday or Sunday may not get processed until the following Monday. Such delays can significantly compromise the quality of the sample.

9 mL CPD Blood (Preferred)

2 mL CPD Bone Marrow (Preferred)

9 mL EDTA Blood

2 mL EDTA Bone Marrow
Turnaround Time: Within 4 weeks
Diagnostic Use and Interpretation

This test is specifically designed to detect aquired mutations in the BCR-ABL transcript. Ph+ patients may develop mutations in the BCR-ABL gene, in response to tyrosine kinase inhibitor treatment, that cause drug resistance. Some of these mutations are known to lack resistance to certain forms or doses of tyrosine kinase inhibitors so a detailed knowledge of the precise mutation in a given patient can be helpful when reassessing treatment.

See also:

BCR-ABL Analysis by Q-PCR

BCR-ABL Transcript Detection by RT-PCR

Contact Information

To contact the Molecular Haematology team please call:

Auckland City Hospital	(09) 307 4949
Lablink	ext 22000
Prof. Peter Browett (Haematologist)	ext 9090-86281
Dr. Imogen Caldwell (Haematologist)	ext 22006
Nikhil Ghallayan (Section Leader)	ext 22005
Molecular Haematology Office	ext 22005

For more information about the Molecular Haematology service at LabPLUS:

Molecular Haematology information page

Last updated at 15:36:59 07/03/2024