Plasma or serum acceptable
Units:
mmol/L
Reference ranges:
| Methyl Bromide: | |
| Non-exposed background concentration: |
< 0.10 |
| Toxic symptoms: |
> 0.30 |
| Bromide Salts: | |
| Non-exposed background concentration: |
< 0.10 |
| Toxic symptoms: |
> 6.0 |
| Potentially lethal: |
> 25.0 |
Uncertainty of Measurement: 10%
Performed fortnightly. Not normally available after hours. If required urgently or after hours, approval of the Chemical Pathologist will be required: contact the laboratory via Lablink.
Principle : Inductively coupled plasma mass spectrometry (ICP-MS)
Instrument : PlasmaQuant MS Elite
Assessment following exposure to inorganic bromide salts (photograph development, therapeutic use) or organic methyl bromide (fumigation).
The interpretation of the bromide concentration measured depends on the source of bromide exposure:
Inorganic bromide salt exposure is assessed directly by measuring the concentration of bromide in the serum.
Organic methyl bromide is more toxic than inorganic bromide salts. Methyl bromide is not measured directly; however it is partially metabolised to inorganic bromide, which is measured.
Some prescribed medications contain bromide or bromide as an impurity in the medication preparation. Some over the counter medications eg cough mixtures contain bromide. Sauna or hot spa disinfectants may also contain bromide.
The reference intervals shown refer to the measured levels (i.e. inorganic bromide).
The half-life of bromide in serum is 12 days.
For more information, please contact the Trace Metals section via Lablink ext 22000
Emails to chemicalpathologist@adhb.govt.nz will receive priority attention from the on-call chemical pathologist.
If the query concerns a specific patient please include the NHI number in your email.
If email is not a suitable option, please contact the on-call chemical pathologist via Lablink (Auckland City Hospital ext. 22000 or 09-3078995).
Individual chemical pathologists may be contacted but will not be available at all times.
After-hours : contact Lablink (Auckland City Hospital ext. 22000 or 09-3078995) or hospital operator for on duty staff after hours.
Dr Samarina Musaad (Clinical Lead) : SamarinaM@adhb.govt.nz ext. 22402
Dr Cam Kyle: CampbellK@adhb.govt.nz ext 22052
Dr Weldon Chiu: WeldonC@adhb.govt.nz ext. 23427
Dr Campbell Heron: CHeron@adhb.govt.nz ext. 23427
Dr Sakunthala Jayasinghe: Sakunthala@adhb.govt.nz ext. 23427