Test Guide Mobile Home
Search: Search

beta-Hydroxybutyrate


Plasma/Serum
Test performed by: LabPLUS Automation


Specimen Collection

Serum/plasma samples must be separated within 6 hours. Separated specimens are

Sample stability:


PST

4.5 mL PST Blood (Preferred)

Micro-PST

0.5 mL Paediatric Micro-PST Blood (Preferred)

Heparin

5 mL Heparin Blood

Plain

4 mL Plain Blood

SST

3.5 mL SST Blood

Microsample

0.5 mL Paediatric Microsample Blood

Micro-heparin

0.5 mL Paediatric Micro-heparin Blood
Reference Intervals

Units: mmol/L

After overnight fast, levels are usually <0.3 mmol/L.

After a 72h fast, levels range from 1 to 8 mmol/L in normal subjects.

Levels from 2 to 20 mmol/L are seen in diabetic ketoacidosis.

Uncertainty of Measurement: 8%



Turnaround Time: Within 3 hours
Assay Method

Principle: Colorimetric

Reagents: Randox RANBUT B-Hydroxybutyrate kit

Analyser: Cobas c502


Diagnostic Use and Interpretation

Betahydroxybutyrate is the prinicipal ketone in plasma. It is used for monitoring the treatment of diabetic ketoacidosis, and for detecting ketosis during fasting or hypoglycemia.

Beta-hydroxybutyrate is not detected by the dipstick test for ketones (which detects only acetoacetic acid).

See Ketones - urine


Contact Information

Emails to chemicalpathologist@adhb.govt.nz will receive priority attention from the on-call chemical pathologist.

If the query concerns a specific patient please include the NHI number in your email.

If email is not a suitable option, please contact the on-call chemical pathologist via Lablink (Auckland City Hospital ext. 22000 or 09-3078995).

Individual chemical pathologists may be contacted but will not be available at all times.

After-hours : contact Lablink (Auckland City Hospital ext. 22000 or 09-3078995) or hospital operator for on duty staff after hours.


Dr Samarina Musaad (Clinical Lead) : SamarinaM@adhb.govt.nz ext. 22402

Dr Cam Kyle: CampbellK@adhb.govt.nz ext 22052

Dr Weldon Chiu: WeldonC@adhb.govt.nz ext. 23427

Dr Campbell Heron: CHeron@adhb.govt.nz ext. 23427

Dr Sakunthala Jayasinghe: Sakunthala@adhb.govt.nz ext. 23427




Last updated at 15:26:00 06/01/2025