Accompanying Maternal blood is required
Microarray and G-Banded Karyotype: (CVS and Amniotic Fluid): 14 - 21 days
Turnaround time may vary depending on sample size, gestational age and cell growth rate.
Fetal blood G-banded karyotype results are available in 3-5 days.
Prenatal rapid aneuploidy screening will primarily be performed by QF-PCR. FISH will be used in some instances when a result is not possible by QF-PCR.
QF-PCR is a molecular technique used for diagnosis of the viable aneuploidies: trisomy 13 (Patau syndrome), trisomy 18 (Edwards syndrome), trisomy 21 (Down syndrome), and sex chromosome aneuploidy including Monosomy X (Turner syndrome). It is used for rapid detection of these aneuploidies prior to microarray analysis.
While the test shares many similarities with rapid aneuploidy FISH, QF-PCR has the added benefit of genotyping the sample and identifying maternal cell contamination.
QF-PCR will not detect copy number variants outside the markers used on chromosomes 13, 18, 21, X and Y and will not detect other genetic alterations.
To contact the Prenatal teams:
| Auckland City Hospital | (09) 307 4949 |
| Lablink | ext 22000 |
| Diagnostic Genetics General Enquiries | ext 22008 |
| Microarray Office | ext 22011 |
| Cytogenetics Office | ext 22012 |
| FISH Office | ext 22008 |
All samples must be collected using sterile technique
Same day delivery preferred
Transport samples >8 degrees Celsius to <24 degrees Celsius