Specimen Collection

• If the specimen is collected from outside Auckland Hospital: Send 2x1.5ml Plasma aliquot, frozen.
• Filtered plasma is unsuitable.

2.7 mL Adult Citrate Blood (Preferred)

1.8 mL Adult 2xCitrate Blood
Reference Intervals

Normal less than 0.5 BU.

Turnaround Time: At least 2 weeks

• Turnaround time within 2-weeks unless URGENT.
• Urgent requests require prior approval from Haematologists.

Diagnostic Use and Interpretation

The Bovine Factor VIII Chromogenic Bethesda Assay is available to screen FVIII inhibitors in patients with Haemophilia A who are receiving Hemlibra (Emicizumab) therapy. Standard clot-based FVIII inhibitor assays cannot accurately determine inhibitor titre levels because of interference of Emicizumab. This assay uses bovine components to measure endogenous FVIII activity which are insensitive to Emicizumab.

Contact Information

Test performed by the Coagulation laboratory: ( Ext 22069 ).
For results, use ward computer or phone LabLINK: 22000 or (09) 307-8995 or 0800 522 758 .

For further information contact the Haematology laboratory (Ext 22067) or:

Dr Nicola Eaddy	Ext 22005
Dr Peter Bradbeer	Ext 22062
Dr Anna Ruskova	Ext 22137
Dr Nikhil Rabade	Ext 22071

Last updated at 13:09:28 11/09/2024