Specimen Collection

4 mL Heparin Blood

Dark green top Heparin tubes are required ,

light green top PST Heparin tubes(containing gel) are NOT suitable.

or

1 mL Paediatric Micro-heparin Blood

Dark green top Heparin tubes are required ,

light green top PST Heparin tubes(containing gel) are NOT suitable.

• Do not refrigerate.
• Tested Mon - Fri only. Samples must be receipted into Labplus midday Friday or on the day prior to public holiday .

For samples sent to LabPlus from outside the Auckland region:

• Sample collection as above, transport at room temperature.
• Sample age limit for testing to be completed is 24 hours.

Reference Intervals

3 subsets of B-cells have been identified with the following phenotype:

1. Naive B-cells , CD19+CD27-IgD+
2. Memory B-cells (unswitched), CD19+CD27+IgD+
3. Memory B-cells (Switched), CD19+CD27+IgD-

Reference Range:

Naive B-cells	57.7 - 79.7 %
Memory B-cells (unswitched),	8.7 - 18.7 %
Memory B-cells (Switched)	5 - 21 %

Turnaround Time: Within 2 weeks
Diagnostic Use and Interpretation

Common Variable Immune Deficiency (CVID) is a heterogeneous group of immune deficient disease. The underlying immunological defect of this syndrome is unknown. CVID patients are characterised by low levels of immunoglobulins and normal to low B-lymphocyte levels.

Contact Information

For further information contact:

• Cell Markers laboratory ext. 22061 or 22075.
• Via Lablink ext. 22000 or (09) 307-8995 or 0800 522 758.
• Out-of-hours on-call 021 753 059.

The Immunopathology team can be reached via email: Immunology@adhb.govt.nz or via Lablink.

• Immunology lab registrar
• Prof. Rohan Ameratunga (Immunopathologist)
• Dr. Maia Brewerton (Immunopathologist)
• Dr. Miriam Hurst (Immunopathologist)
• Dr. Hilary Longhurst (Immunopathologist)

Last updated at 11:14:27 06/05/2025