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Tricyclic antidepressant drugs


Serum
Test performed by: LabPLUS High Performance Liquid Chromatography


Specimen Collection

Tubes containing gel (SST and PST) are NOT acceptable

Ordering recommendation:

Tricyclic antidepressants include amitriptyline, clomipramine, desipramine, doxepin, imipramine, nortriptyline and Dothiepin.

Please specify drug of interest on request form.


Plain

4 mL Plain Blood (Preferred)

Microsample

1 mL Paediatric Microsample Blood (Preferred)

Heparin

4 mL Adult Heparin Blood
Reference Intervals

For therapeutic ranges please see individual drugs.



Turnaround Time: Within 1 week

Analysed weekly


Assay Method

Principle : High performance liquid chromatography with photodiode array detection (HPLC-PDA)


Contact Information

Emails to chemicalpathologist@adhb.govt.nz will receive priority attention from the on-call chemical pathologist.

If the query concerns a specific patient please include the NHI number in your email.

If email is not a suitable option, please contact the on-call chemical pathologist via Lablink (Auckland City Hospital ext. 22000 or 09-3078995).

Individual chemical pathologists may be contacted but will not be available at all times.

After-hours : contact Lablink (Auckland City Hospital ext. 22000 or 09-3078995) or hospital operator for on duty staff after hours.


Dr Samarina Musaad (Clinical Lead) : SamarinaM@adhb.govt.nz ext. 22402

Dr Cam Kyle: CampbellK@adhb.govt.nz ext 22052

Dr Weldon Chiu: WeldonC@adhb.govt.nz ext. 23427

Dr Campbell Heron: CHeron@adhb.govt.nz ext. 23427

Dr Sakunthala Jayasinghe: Sakunthala@adhb.govt.nz ext. 23427



Specimen Transport Instructions for Referring Laboratories

Centrifuge and separate blood as soon as possible after collection.

If sending within Auckland then sample can be sent refrigerated (2-8 degrees) or at ambient temperature (8-24 degrees).

If sending from outside Auckland then send sample refrigerated (2-8 degrees).

Note: If temperature during shipping is likely to exceed 24 degrees then results may not always be reliable.



Last updated at 15:26:00 06/01/2025