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Tricyclic antidepressant drugs


Serum
Test performed by: LabPLUS High Performance Liquid Chromatography


Specimen Collection

Tubes containing gel (SST and PST) are NOT acceptable

Ordering recommendation:

Tricyclic antidepressants include amitriptyline, clomipramine, desipramine, doxepin, imipramine, nortriptyline and Dothiepin.

Please specify drug of interest on request form.


Plain

4 mL Plain Blood (Preferred)

Microsample

1 mL Paediatric Microsample Blood (Preferred)

Heparin

4 mL Adult Heparin Blood
Reference Intervals

For therapeutic ranges please see individual drugs.



Turnaround Time: Between 1 week and 2 weeks

Analysed weekly or fortnightly.


Assay Method

Principle : High performance liquid chromatography with photodiode array detection (HPLC-PDA)


Contact Information

The chemical pathology team can be reached via email: chemicalpathologist@adhb.govt.nz or via Lablink (09) 307 4949 ext 22000 or 09-3078995

Emails will receive priority attention from the on-call chemical pathologist. Include the patients NHI.

After-hours: contact Lablink (Auckland City Hospital ext. 22000 or 09-3078995) or hospital operator for on duty staff after hours .



Specimen Transport Instructions for Referring Laboratories

Centrifuge and separate blood as soon as possible after collection.

If sending within Auckland then sample can be sent refrigerated (2-8 degrees) or at ambient temperature (8-24 degrees).

If sending from outside Auckland then send sample refrigerated (2-8 degrees).

Note: If temperature during shipping is likely to exceed 24 degrees then results may not always be reliable.



Last updated at 11:42:03 16/01/2026