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Sulphonylurea Drug screen


Serum
Test performed by: LabPLUS High Performance Liquid Chromatography


Specimen Collection

Test not available outside normal working hours.

Tubes containing gel (SST and PST) are NOT acceptable


Plain4 mL Plain Blood (Always Required)
Turnaround Time: Within 1 week

Performed Weekly.


Assay Method

Principle : High performance liquid chromatography


Diagnostic Use and Interpretation

The presence of sulphonylurea drugs should be excluded in the patient who presents with a suspected insulinoma. Hypoglycaemia may occur in both diabetic and non-diabetic patients and may be caused by the surreptitious use of sulphonylurea drugs or insulin.

The clearance of the Sulphonylurea drugs is fast. They will only be detectable for 1-2 days after dosage. The composition of the metabolites is not known.

This test is not to be used for Therapeutic drug monitoring and guidance of doses


Contact Information

Emails to chemicalpathologist@adhb.govt.nz will receive priority attention from the on-call chemical pathologist.

If the query concerns a specific patient please include the NHI number in your email.

If email is not a suitable option, please contact the on-call chemical pathologist via Lablink (Auckland City Hospital ext. 22000 or 09-3078995).

Individual chemical pathologists may be contacted but will not be available at all times. 

After-hours : contact  Lablink (Auckland City Hospital ext. 22000 or 09-3078995) or hospital operator for on duty staff after hours.


Dr Samarina Musaad (Clinical Lead) : SamarinaM@adhb.govt.nz ext. 22402 

Dr Cam Kyle: CampbellK@adhb.govt.nz   ext 22052 

Dr Weldon Chiu: WeldonC@adhb.govt.nz   ext. 23427 

Dr Campbell Heron: CHeron@adhb.govt.nz   ext. 23427



Specimen Transport Instructions for Referring Laboratories

Aliquot : 2 mL (minimum 1 mL) serum.

Centrifuge and separate blood as soon as possible after collection.

If sending within Auckland then sample can be sent refrigerated (2-8 degrees) or at ambient temperature (8-24 degrees).

If sending from outside Auckland then send sample refrigerated (2-8 degrees).

 

Note: If temperature during shipping is likely to exceed 24 degrees then results may not always be reliable.



Last updated at 09:25:30 22/01/2024