Separate serum within 4 hours of collection. Store and ship at 4 o C within 12 hours of collection. Otherwise freeze serum then send sample frozen.
Please send 2 X 3.5 mL SST tube
Please send 2 X 4 mL plain tube
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Results are given as a chance of the conditions screened for. The screening threshold is 1:300 for aneuploidies, for example; - Low chance would be 1:301 -1:100,000. - Increased chance would be 1:5 - 1:300. An accurate estimated date of delivery (EDD) is critical to this risk estimate. |
Results may be delayed if there is incomplete or incorrect information on the request form.
AutoDELFIA, Revity
All tests have UOM of 10%
Antenatal screening for Down syndrome and other genetic conditions is a crucial aspect of prenatal care, providing valuable information to expectant mothers and families. This screening allows for an estimate of the likelihood that a baby may have Down syndrome or other genetic anomalies. The information gained from these screenings empowers women and families to make informed choices about the care and management of their pregnancy and birth.
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First Trimester Screening:
- Collection Timing: Blood must be collected when the patient is between 9 weeks and 13 weeks 6 days gestation. Nuchal translucency is to be performed with in the same time frame however is best taken between 12 weeks and 13 weeks 6 days.
- Components: Measurement of PAPP-A (pregnancy-associated plasma protein-A) and free B-hCG (beta-human chorionic gonadotropin).
- Additional Component: Nuchal translucency measurement.
- Purpose: Assess the risk of Down syndrome and other chromosomal conditions.
- Availability: Funded by the NSU to New Zealand residents or patient with an appropriate visa. Non- residents are not funded, however is available at a cost to the patient.
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Second Trimester Screen:
- Collection Timing: Blood must be collected when the patient is between 14 weeks and 20 weeks 6 days gestation.
- Components: Measurement of AFP (alpha-fetoprotein), free B-hCG, unconjugated estriol (UE3), and Inhibin A.
- Additional Component: Nuchal translucency measurement, if provided.
- Purpose: Assess the risk of Down syndrome and other chromosomal conditions.
- Availability: Funded by the NSU to New Zealand residents or patient with an appropriate visa. Non- residents are not funded, however is available at a cost to the patient.
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Serum Integrated Screening:
- Components: Measurement of PAPP-A in the first trimester, followed by measurements of AFP, unconjugated estriol, free B-hCG, and Inhibin A in the second trimester.
- Integration: Results from both trimesters are combined to produce a comprehensive risk assessment.
- Purpose: Assess the risk of Down syndrome and other chromosomal conditions when a nuchal translucency measurement could not be obtained or provided.
- Availability: Funded by the NSU to New Zealand residents or patient with an appropriate visa. Non- residents are not funded, however is available at a cost to the patient.
- Fully Integrated Screening :
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Components: Measurement of PAPP-A in the first trimester, followed by measurements of AFP, unconjugated estriol, free B-hCG, and Inhibin A in the second trimester.
- Additional Component: Nuchal translucency measurement.
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Integration: Results from both trimesters are combined to produce a comprehensive risk assessment.
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Purpose: Assess the risk of Down syndrome and other chromosomal conditions.
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Availability: Not funded by NSU, however is available at a cost of $190 + GST to the patient
- Further Note:
- These costs do not include the radiographers fee where an ultrasound scan has been performed
It's essential to note that these screening tests provide a risk assessment and are not diagnostic . Further diagnostic tests, such as amniocentesis or chorionic villus sampling (CVS), may be recommended for a definitive diagnosis if an increased chance result is obtained from screening.
Via Lablink (09) 307 4949 ext. 22000 or 0800 522 758 or coordinator (09) 307 4949 ext. 23124 or 021 884 621
The scientist responsible for this test is Tamara Butler, email tamara@adhb.govt.nz
Separate serum within 4 hours of collection.
Store and ship at 4C within 12 hours of collection. Otherwise freeze serum then send sample frozen.