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IL28B rs12979860 C>T SNP Analysis
Short Description : IL-28B Testing
Also known as : [IL-28B Genotyping]


DNA
Test performed by: LabPLUS - Dept. Diagnostic Genetics - Molecular Haematology


For more inforamtion about the Molecular Haematology service at LabPLUS:

Molecular Haematology information page


Specimen Collection

Note: Whole blood samples are required for this test. Please DO NOT send plasma or serum samples for testing.

Note: All samples should be forwarded to LabPlus at room temperature within 24hours.


CPD3 mL CPD Blood (Preferred)
EDTA3 mL EDTA Blood
Turnaround Time: Within 2 weeks, 4 days
Diagnostic Use and Interpretation

In patients infected with hepatitis C virus Genotype 1, studies have shown an association of a single nucleotide polymorphism (rs12979860) near the IL28B gene and response to current hepatitis C therapy (pegylated interferon plus ribavirin) [Ge et al. Nature (2009) 461;399-401]. There are two different alleles at this locus - the "C" and the "T" allele. The CC genotype is associated with a higher rate of sustained response to this treatment (i.e. cure) than the CT or TT genotypes.


Contact Information

To contact the Molecular Haematology team please call:

Auckland City Hospital   (09) 307 4949
Lablink   ext 22000
Dr Ed Gane  (Hepatologist)     ext 22922
Neil Van de Water (Scientific Officer)    ext 22006
Molecular Haematology Lab   ext 22005



Last updated at 10:49:53 18/06/2013