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Haemophilus influenza B Serology


Blood
Test performed by: LabPLUS VIM Infectious Disease Serology


Specimen Collection
SST3.5 mL SST Serum (Preferred)
Plain4 mL Plain Serum
Microsample500 uL Microsample Serum
Reference Intervals

Assay measuring range: 9.00-0.11 mg/L

Interpretation provided with result.

Uncertainty of Measurement:   20%



Turnaround Time: Between 2 weeks and 4 weeks
Diagnostic Use and Interpretation

Positive results in neonatal specimens (£ 6 months of age) must be interpreted with caution due to passive transfer of maternal IgG

Pre- and post vaccination samples should be run simultaneously

Results may be used to aid a diagnosis of immunodeficiency.

Results from this assay are not diagnostic proof of lack protection / protection against H.influenzae infection or the presence or absence of immunodeficiency.

Haemophilus influenzae (Hib)is an encapsulated Gram negative bacterium which can cause a range of conditions including meningitis, septicaemia, cellulites, epiglottis, pneumonia and septic arthritis. Hib infections are common in children under five years of age where it is the major cause of bacterial meningitis. A protective level of 0.15mg/L is generally accepted, however, as responses are age related, paediatric protective levels may vary from this concentration. This assay will be used as an aid to identify individuals with suspected immunodeficiency. Results of this assay are correlated with vaccine responses to diphtheria toxoid, HBsAg and tetanus toxoid to determine the probable type of immunodeficiency

References

Binding Site insert for Haemophilus influenzae IgG EIA kit.


Contact Information

For further information contact the laboratory (09) 307 4949 ext 22000 or:

Associate Professor Rohan Ameratunga , Immunopathologist: Locator 93-5724

Or the LabPLUS Immunology Team



Last updated at 13:58:14 26/04/2019