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HMMA
Also known as : [Hydroxymethoxy-mandelic acid],[VANILLYL MANDELIC ACID],[VMA]

Urine
Test performed by: LabPLUS High Performance Liquid Chromatography

Specimen Collection

HMMA is no longer offered. Please request urine dopamine and HVA for diagnosis of neuroblastoma, and metanephrines (urine/plasma) for phaeochromocytoma/paraganglioma.


Reference Intervals

24 Hour Urine:

Age

24 hr HMMA

HMMA / Creatinine

Units:

 (umol/d)

  (umol/mmol)

10 - < 15 years 

<32

<6

15 years and older 

<47

<5

Random urine:

Age

HMMA / Creatinine

(umol/mmol)


< 3 months

<21

3 months - < 1 year 

<14

1 year - < 2 years 

<15

2 years - < 5 years 

<11

5 years - < 10 years

<8

10 years - < 15 years 

<4

Uncertainty of Measurement:   12%



Turnaround Time: Within 1 week
Diagnostic Use and Interpretation

Urine metanephrines   or plasma metanephrines are the primary tests of choice for diagnosing phaeochromocytomas.

Urine dopamine and HVA ( homovanillic acid) are the primary tests of choice for diagnosing neuroblastomas.

HMMA may be helpful in some cases where results of the primary tests are inconclusive.

See also:


Contact Information

Emails to chemicalpathologist@adhb.govt.nz will receive priority attention from the on-call chemical pathologist.

If the query concerns a specific patient please include the NHI number in your email.

If email is not a suitable option, please contact the on-call chemical pathologist via Lablink (Auckland City Hospital ext. 22000 or 09-3078995).

Individual chemical pathologists may be contacted but will not be available at all times. 

After-hours : contact  Lablink (Auckland City Hospital ext. 22000 or 09-3078995) or hospital operator for on duty staff after hours.


Dr Samarina Musaad (Clinical Lead) : SamarinaM@adhb.govt.nz ext. 22402 

Dr Cam Kyle: CampbellK@adhb.govt.nz   ext 22052 

Dr Weldon Chiu: WeldonC@adhb.govt.nz   ext. 23427 

Dr Campbell Heron: CHeron@adhb.govt.nz   ext. 23427




Last updated at 09:25:30 22/01/2024