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Fibrinogen Assay

Blood
Test performed by: LabPLUS Coagulation


Test performed by the  Coagulation laboratory: ( Ext 22069 ).
For results, use ward computer or phone LabLINK:   22000 or (09) 307-8995 or 0800 522 758 .

Specimen Collection
Citrate2.7 mL Citrate Blood

or


Citrate1.8 mL Citrate Blood

or


Micro-citrate1 mL Paediatric Micro-citrate Blood


Reference Intervals

Uncertainty of Measurement : 8%

Units: g/L

Age Range            Either Sex              
All 1.5 - 4.0 [1]

 

[1]

  • Antenatal:          2.0 - 6.5 g/L
  • Newborn :          near normal adult levels.



Turnaround Time: Within 2 hours
Diagnostic Use and Interpretation

Increased

As part of acute phase response. e.g. acute and chronic inflammation, liver disease, pregnancy, compensated intravascular coagulation, nephrotic syndrome.

Decreased

In congenital hypofibrinogenaemia (rare), DIC, advanced liver disease, lytic therapy, L-asparaginase therapy. Acquired dysfibrinogenaemia occurs mainly in association with liver and renal disease. Bleeding is rarely a problem. Typically, thrombin clotting time is long and /or fibrinogen is low.

Result interpretation can be difficult in the presence of dysfibrinogenaemia, high FDP and high dose heparin, when fibrinogen can appear (falsely) low.

NOTE: In consumptive processes serial fibrinogen levels are of more use than single point assays.

See

Thrombin Clotting Time


Contact Information

For further information contact the Haematology laboratory (Ext 22067) or:

Dr Nicola Eaddy                                    Ext 22005
Dr Peter Bradbeer                                   Ext 22062  
Dr Anna Ruskova                                   Ext 22137
Dr Nikhil Rabade                                   Ext 22071



Last updated at 10:31:53 18/09/2024