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Methaemoglobin
Short Description : Methahaemoglobin


Whole Blood
Test performed by: LabPLUS Automation


Specimen Collection

Stability: up to 72h at 4C.  Store on ice if transit time to the laboratory is greater than 2 hours. 
 
Please phone laboratory to advise of urgency criteria.


Heparin5 mL Heparin Whole Blood (Always Required)
Micro-heparin0.5 mL Paediatric Micro-heparin Whole Blood
Reference Intervals

Units: % of total haemoglobin

Ranges:

Premature neonate

0.08- 4.4% 

Full term neonate

0.0  - 2.8%

Adult

0.2  - 1.5%

 Toxic level

> 15% 

   

    Uncertainty of Measurement:   0.5% up to a concentration of 20% of total haemoglobin



Turnaround Time: Within 2 hours
Diagnostic Use and Interpretation

Methaemoglobin is haemoglobin with the iron oxidised to its ferric state. It is unable to bind oxygen, and causes hypoxia and cyanosis at high concentrations.

It is increased in methaemoglobin reductase deficiency .

Also increased due to drugs: chloroquine, isoniazid, nitrates, nitrites, sulphonamides, benzocaine, aniline dyes. Fetal hemoglobin converts to methaemoglobin more readily than adult haemoglobin; infants have an increased susceptibility to forming methaemoglobin.

See  Haemoglobin M

See  Methaemoglobin Reductase


Contact Information

The chemical pathology  team can be reached via email: chemicalpathologist@adhb.govt.nz or via Lablink  (09) 307 4949 ext 22000 or 09-3078995

Emails will receive priority attention from the on-call chemical pathologist. Include the patients NHI.

After-hours: contact  Lablink (Auckland City Hospital ext. 22000 or 09-3078995) or hospital operator for on duty staff after hours .




Last updated at 11:42:03 16/01/2026