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Methaemoglobin
Short Description : Methahaemoglobin


Whole Blood
Test performed by: LabPLUS Automation


Specimen Collection

Stability: up to 72h at 4C.  Store on ice if transit time to the laboratory is greater than 2 hours. 
 
Please phone laboratory to advise of urgency criteria.


Heparin5 mL Heparin Whole Blood (Always Required)
Micro-heparin0.5 mL Paediatric Micro-heparin Whole Blood
Reference Intervals

Units: % of total haemoglobin

Ranges:

Premature neonate

0.08- 4.4% 

Full term neonate

0.0  - 2.8%

Adult

0.2  - 1.5%

 Toxic level

> 15% 

   

    Uncertainty of Measurement:   0.5% up to a concentration of 20% of total haemoglobin



Turnaround Time: Within 2 hours
Diagnostic Use and Interpretation

Methaemoglobin is haemoglobin with the iron oxidised to its ferric state. It is unable to bind oxygen, and causes hypoxia and cyanosis at high concentrations.

It is increased in methaemoglobin reductase deficiency .

Also increased due to drugs: chloroquine, isoniazid, nitrates, nitrites, sulphonamides, benzocaine, aniline dyes. Fetal hemoglobin converts to methaemoglobin more readily than adult haemoglobin; infants have an increased susceptibility to forming methaemoglobin.

See  Haemoglobin M

See  Methaemoglobin Reductase


Contact Information

Emails to chemicalpathologist@adhb.govt.nz will receive priority attention from the on-call chemical pathologist.

If the query concerns a specific patient please include the NHI number in your email.

If email is not a suitable option, please contact the on-call chemical pathologist via Lablink (Auckland City Hospital ext. 22000 or 09-3078995).

Individual chemical pathologists may be contacted but will not be available at all times. 

After-hours : contact  Lablink (Auckland City Hospital ext. 22000 or 09-3078995) or hospital operator for on duty staff after hours.


Dr Samarina Musaad (Clinical Lead) : SamarinaM@adhb.govt.nz ext. 22402 

Dr Cam Kyle: CampbellK@adhb.govt.nz   ext 22052 

Dr Weldon Chiu: WeldonC@adhb.govt.nz   ext. 23427 

Dr Campbell Heron: CHeron@adhb.govt.nz   ext. 23427

Dr Sakunthala Jayasinghe: Sakunthala@adhb.govt.nz ext. 23427




Last updated at 15:26:00 06/01/2025