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Alpha Thalassaemia Screen

Blood
Test performed by: LabPLUS Special Haematology


Test performed by the Special Haematology laboratory: (Ext 22065) .
For results, use ward computer or phone Lablink:   22000 or (09) 307-8995 or 0800 522 758 .

Specimen Collection
EDTA1 mL Adult EDTA Blood

If sample is being sent to LabPlus from outside the Auckland region, please ensure it arrives within 24 hrs of collection for optimal testing conditions.


EDTA500 uL Paediatric EDTA Blood
Reference Intervals

Normal = Negative



Turnaround Time: Within 1 week

Analysed as part of

Haemogloginopathy Screen


Assay Method

Effective from 9.9.15

Immunochromatographic assay for the determination of Alpha thalassaemia by the detection of HbBarts.


Diagnostic Use and Interpretation

The Alpha Thalassaemia screen employs an immunochromatographic assay to detect small amounts of Hb Barts which can be found in the blood of some alpha thalassaemia carriers. This method replaced the Brilliant Cresyl Blue stain for HbH from Sept 2015.


Sensitivity for alpha thalassaemia trait is between 97% - 100%, depending on the genotype of the alpha thalassaemia trait. A negative result therefore does not exclude alpha thalassaemia trait, particularly for one-gene deletion alpha thalassemia heterozygous state (carrier of one-gene deletion alpha thalassemia).  If alpha thalassaemia trait is suspected but Alpha Thalassaemia screen is negative, please discuss with a Haematologist on the need for molecular testing.
  


Contact Information

For further information contact the Haematology laboratory (Ext 22067) or:

Dr Nicola Eaddy                                    Ext 22071
Dr Peter Bradbeer                                   Ext 22062
Dr Anna Ruskova                                   Ext 22137



Last updated at 15:21:03 14/11/2023