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Calreticulin Exon 9 Mutation Analysis
Short Description : CALR Exon 9 Mutation Analysis

DNA/RNA
Test performed by: LabPLUS - Dept. Diagnostic Genetics - Molecular Haematology

Specimen Collection
CPD2 mL CPD Blood (Preferred)
EDTA2 mL EDTA Blood
Turnaround Time: Between 2 weeks and 4 weeks
Diagnostic Use and Interpretation

CALR exon 9 mutations are found in approximately 65% of non-JAK2 mutated essential thrombocythemia and 85% of non-JAK2 mutated primary myelofibrosis. In both ET and PMF, CALR mutations are associated with a lower risk of thrombosis and longer overall survival than JAK2 mutations. 

Klamfl et al. (2013) NEJM, 369(25):2379-2390 


Contact Information

To contact the Molecular Haematology team please call:

Auckland City Hospital   (09) 307 4949
Lablink   ext 22000
Prof. Peter Browett (Haematologist)     ext 9090-86281
Dr. Imogen Caldwell (Haematologist)   ext 22006
Nikhil Ghallayan (Section Leader)   ext 22005
Molecular Haematology Office   ext 22005

For more information about the Molecular Haematology service at LabPLUS:

Molecular Haematology information page



Last updated at 15:36:59 07/03/2024